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Unless you have cardio side effects such as high blood pressure, heart palpitations etc. Instead of over - the - counter analgesics, prescription analgesics that are more appropriate for migraine headaches are often prescribed Many doctors will have samples of Imitrex and other migraines meds to give to those who dont have Is imitrex an over the counter drug? Influenza Season, United who can buy imitrex States click for info. It’s also available as a generic drug. PSA is hosting a webinar on managing migraines with over-the-counter provision of triptans on (27 January, 8:30pm AEDT). [2] Effects generally occur within three hours. [1] It is taken by mouth, in the nose, or by injection under the skin. I would ask your doctor for a Sumatriptan prescription. Imitrex is available as oral tablets, a nasal spray, and as an injection. I myself take Sumatriptan subcutaneously. 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